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dougsherwood1320 Black Belt 1st Degree


Joined: 01 Oct 2003 Posts: 1250 Location: YUMA, ARIZONA
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Posted: Wed Oct 29, 2003 12:17 am Post subject: I'll bite |
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I may sound nieve but, after reading some stuff about folding, I am still unclear as to what it is. I am a hardware engineer and do not understand.
Could someone help me?  _________________ SOME THINGS MUST BE BELIEVED TO BE SEEN
MEMBER- MOTHERBOARDS.ORG FOLDING TEAM
>>>>>>>>>1,000,000 POINTS<<<<<<<<< |
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YouGiveMeRash!!! Black Belt 5th Degree


Joined: 23 Jun 2002 Posts: 6772 Location: Fast, Cheap, and Reliable- You can only choose 2
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Posted: Wed Oct 29, 2003 12:31 am Post subject: |
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Here is what it is all about:
http://www.tech-report.com/etc/folding/ _________________ Main rig: 1/2" ID Water Cooled Lian-Li V2000B, Abit IP35 Pro, Intel C2D E6750@ -3.4ghz 1.3375v, Mushkin 2gb DDR2-800 996576, one terabyte storage, evga 7900GS KO w/ Zalman VF700-AlCu cooler, Swiftech Apogee GT water block, Ultra X2 550w PSU
Laptop: Asus Z70VA, Pentium M 725 1.6@ -2.13ghz (pinmod), ATI X700 Pro, 1680x1050 native res., bluetooth, the works... |
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dougsherwood1320 Black Belt 1st Degree


Joined: 01 Oct 2003 Posts: 1250 Location: YUMA, ARIZONA
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Posted: Wed Oct 29, 2003 12:59 am Post subject: ? |
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OK, I have read what they have to say and I do not understand what biology has to do with computers. _________________ SOME THINGS MUST BE BELIEVED TO BE SEEN
MEMBER- MOTHERBOARDS.ORG FOLDING TEAM
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Aussie Mobo-fu Master


Joined: 22 Nov 1999 Posts: 10244 Location: Mackay, Queensland, Australia
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Posted: Wed Oct 29, 2003 4:40 am Post subject: |
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http://www.stanford.edu/group/pandegroup/folding/
| Quote: | Our goal: to understand protein folding, protein aggregation, and related diseases
What are proteins and why do they "fold"? Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out their biochemical function, they remarkably assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, remains a mystery. Moreover, perhaps not surprisingly, when proteins do not fold correctly (i.e. "misfold"), there can be serious effects, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, and Parkinson's disease.
What does Folding@Home do? Folding@Home is a distributed computing project which studies protein folding, misfolding, aggregation, and related diseases. We use novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. This has allowed us to simulate folding for the first time, and to now direct our approach to examine folding related disease. |
http://www.stanford.edu/group/pandegroup/folding/science.html
| Quote: | WHY IS PROTEIN FOLDING SO DIFFICULT TO UNDERSTAND?
It's amazing that not only do proteins self-assemble -- fold -- but they do so amazingly quickly: some as fast as a millionth of a second. While this time is very fast on a person's timescale, it's remarkably long for computers to simulate.
In fact, it takes about a day to simulate a nanosecond (1/1,000,000,000 of a second). Unfortunately, proteins fold on the tens of microsecond timescale (10,000 nanoseconds). Thus, it would take 10,000 CPU days to simulate folding -- i.e. it would take 30 CPU years! That's a long time to wait for one result!
A SOLUTION: DISTRIBUTED DYNAMICS
To solve the protein folding problem, we need to break the microsecond barrier. Our group has developed a new way to simulate protein folding which can break the microsecond barrier by dividing the work between multiple processors in a new way -- with a near linear speed up in the number of processors. Thus, with 1000 processors, we can break the microsecond barrier and help unlock the mystery of how proteins fold. |
Aussie _________________ Our lives begin to end the day we become silent about things that matter - Martin Luther King |
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