Many brands/models of mobo types that can support a complex RAID array. But whenever the OS detects a major change in hardware or features, it will self-destruct. Best option would be to find another brand but same model of mobo, to avoid the hassle of reinstalling all programming.
has a few listings similar to that Asus P5B model.
F@H.. to solve mankind's maladies.. in our lifetimes!