Water cooling question

[Wizard4169]

This may be a dumb question, but I'm going to ask it anyway. I'm building a new machine with a single-loop liquid cooling system with water blocks on the CPU and the video card. My question is, will it make any significant difference which water block comes first? I looked around a little and couldn't seem to find any relevant info, so I decided to just ask here.

The CPU is an i7-4770K and I am eventually planning to try some overclocking, so I expect it to run a little on the warm side. My thinking was that I should probably route the coolant through the CPU first, but I'd welcome any input anyone can offer. (Hey, nobody here at the Mother Board has steered me wrong yet!)

[Roach412]

it doesn't really much matter...but is arguable for either way. i've almost always seen CPU first then GPU. most cite that the GPU is designed to handle higher temps - and is the hotter of the two (thus, put the hottest component last so you don't incur heat from the first onto the second).

whatever keeps the loop the smallest and most efficient is your best bet.

-Roach